Physiology Paper-2 (Supplementary), 2021 MBBS Batch ABVMU Lucknow

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, UTTAR PRADESH
MBBS I ST PROFESSIONAL SUPPLEMENTARY EXAMINATION
PHYSIOLOGY - PAPER - II

TIME: 3 Hrs
Max. Marks: 100

Note: Attempt all questions. Answer Section - A and Section - B in separate answer books. All parts of a question should be answered together.

PART - A

PAPER CODE: 2322130002

Q.1 Long Answer Question (1 x 15 = 15 Marks)

A 65-year-old male presented with complaints of slowed movements, fatigue, hand tremors, and slurring of speech. On examination, bradykinesia, hypertonia with cogwheel rigidity was present. Shuffling gait, resting tremors with an expressionless face were seen.

a) What is the probable diagnosis? (3 Marks)
b) Explain the pathophysiology of the above condition. (6 Marks)
c) Explain the physiological basis of different signs and symptoms seen in this condition. (6 Marks)

Q.2 Short Notes Questions (within 500 words) (3 x 5 = 15 Marks)

a) Properties of Synapse
b) Functions of Hypothalamus
c) Factors affecting Glomerular Filtration rate

Q.3 Short Answer Questions (within 100 words) (5 x 2 = 10 Marks)

a) REM Sleep

b) Tests of cerebellar dysfunction

c) Color blindness

d) Tests of taste sensation

e) Weber`s Test

Q.4 Multiple Choice Questions (1 x 10 = 10 Marks)

1. Phantom limb sensations are best described by:
   a) Weber Fechner Law
   b) Law of Specific Nerve Energies
   c) Law of Projection
   d) None of the above

2. Modality that is lost on the ipsilateral side in Brown Sequard syndrome:
   a) Pain
   b) Crude touch
   c) Temperature
   d) Proprioception

3. Theta wave is concerned with:
   a) Functions of brainstem
   b) Functions of hippocampus
   c) Functions of cerebellum
   d) Spinal cord

4. Origin of cortisol is present in:
   a) Zona glomerulosa
   b) Zona fasciculata
   c) Zona reticularis
   d) Spinal cord

5. Main excitatory neurotransmitter in CNS is:
   a) Aspartate
   b) Glycine
   c) Glutamate
   d) Acetylcholine

6. Olfactory receptors are:
   a) Rapidly adapting
   b) Mechanoreceptors
   c) Rapidly replaced
   d) Located in cribriform plate

7. Thalamus is a relay center for all of the following sensations EXCEPT:
   a) Smell
   b) Pain
   c) Temperature
   d) Proprioception

8. Excretion of dilute or concentrated urine mainly depends on:
   a) Levels of Antidiuretic Hormone
   b) Levels of Renin
   c) Active Sodium absorption from Proximal tubules
   d) Hydrogen secretion in Distal tubule

9. Thyrotropin secretion from kidneys is stimulated by:
   a) Rise in tissue pH
   b) Rise in Hb
   c) Decreased Tissue pO2 concentration
   d) Increased Tissue pCO2 Concentration

10. Major portion of Glomerular filtrate gets absorbed in:
    a) DCT
    b) Loop of Henle
    c) PCT
    d) Collecting ducts

PART - B PAPER CODE: 2322130002

Q.1 Long Answer Question (1 x 15 = 15 Marks)

A 40-year-old male presented with complaints of weight loss, increased appetite, thirst, and urination. On investigation, his Random Blood sugar was 210 mg/dl and dipstick test for glucose in urine was positive.

a) What is the probable diagnosis? (3 Marks)
b) Which hormone is responsible for this condition? (3 Marks)
c) Explain physiological basis of the clinical signs and symptoms. (6 Marks)
d) Describe physiological actions of the hormone responsible for this condition. (3 Marks)

Q.2 Short Notes Questions (within 500 words) (3 x 5 = 15 Marks)

a) Errors of refraction
b) Synthesis and functions of thyroid hormones
c) Mechanism of oral contraceptive pills

Q.3 Short Answer Questions (within 100 words) (5 x 2 = 10 Marks)

a) Obligatory Urine Volume
b) Draw well-labelled diagram of a nephron
c) Function of Sertoli cells
d) Physiological Action of Parathyroid hormone
e) Neuro-Immune-Endocrine Axis

Q.4 Multiple Choice Questions (1 x 10 = 10 Marks)

1. Hormone secreted by Posterior pituitary is:
   a) Prolactin
   b) Thyroid Stimulating Hormone
   c) Oxytocin
   d) Luteinizing Hormone

2. ACTH level is highest during:
   a) Early morning
   b) Afternoon
   c) Evening
   d) Night

3. Difference between Pituitary dwarf and Thyroid dwarf is:
   a) Physical Growth
   b) Mental Growth
   c) Skeletal Growth
   d) Reproduction

4. Secretion of which of the following hormone is decreased during stress:
   a) Adrenalin
   b) ACTH
   c) Cortisol
   d) Insulin

5. Ovulation usually takes place:
   a) 7 days prior to menses
   b) 7 days after menses
   c) 14 days before menses
   d) 14 days after menses

6. Urine pregnancy test detects presence of which hormone?
   a) HCG
   b) LH
   c) Progesterone
   d) Estrogen

7. Average weight gain during pregnancy is:
   a) 2-3 kg
   b) 5-8 kg
   c) 8-13 kg
   d) 15 kg

8. Exercise that strengthens the muscle is:
   a) Isotonic
   b) Isometric
   c) Aerobic
   d) Anaerobic

9. First physiological response to high environmental temperature is:
   a) Vasodilation
   b) Sweating
   c) Piloerection
   d) Shivering

10. Vitamin E plays an important role in body as:
    a) Anticoagulant
    b) Procoagulant
    c) Free radical generator
    d) Antioxidant

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