Physiology Paper-2 (Main), 2022 MBBS Batch ABVMU Lucknow

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW

MBBS DEGREE EXAMINATION - 1st PROFESSIONAL - NOV. - 2023

PHYSIOLOGY - PAPER - II

SECTION A - Multiple Choice Questions (MCQs)

PAPER CODE: 2312130002
SET: A

Note: Choose one correct answer in the OMR sheet provided. No overwriting should be done.

Time: 20 Minutes
(20 × 1 = 20 MARKS)

• 1. Capacitation of sperms takes place in:
  a) Seminiferous tubules
  b) Vas deferens
  c) Epididymis
  d) Uterus

• 2. Ductal growth in mammary gland during pregnancy is predominantly due to:
  a) Prolactin
  b) Estrogen
  c) Human Placental Lactogen
  d) Progesterone

• 3. Which of the following hormones does NOT have an intracellular receptor?
  a) Cortisone
  b) Aldosterone
  c) Thyroxine
  d) Adrenaline

• 4. Property of specificity of nerve fibers for transmitting only one modality of sensation is called:
  a) Law of Projection
  b) Labeled line principle
  c) Spatial summation
  d) Weber Fechner law

• 5. Helicotrema is a communication between:
  a) Cochlea and semicircular canal
  b) Vestibule and semicircular canal
  c) Scala vestibuli and scala tympani
  d) Scala media and cochlea

• 6. The intrafusal fibers of muscle spindle are supplied by:
  a) Motor neuron
  b) Dorsal root neuron
  c) Alpha motor neuron
  d) Gamma motor neuron

• 7. Planning of sequential movements occurs at:
  a) Vestibulocerebellum
  b) Cerebrocerebellum
  c) Spinocerebellum
  d) Flocculonodular lobe

• 8. The inhibitor of glucagon secretion:
  a) Amino acids
  b) Exercise
  c) Somatostatin
  d) Cortisol

• 9. Which of the following substances CANNOT cross the blood-brain barrier?
  a) Metabolic wastes, toxins, K⁺
  b) O₂, CO₂, and H₂O₂
  c) Fats, fatty acids, fat-soluble substances
  d) Alcohol, nicotine, anaesthetics

• 10. What part of the brain subconsciously provides the appropriate pattern of smooth coordinated skeletal muscle contraction for movements?
  a) The cerebellum
  b) The brainstem
  c) The cerebrum
  d) The diencephalon

• 11. Crossed extensor reflex is a:
  a) Withdrawal reflex
  b) Monosynaptic reflex
  c) Stretch reflex
  d) Local static reflex

• 12. Membrane which divides cochlear bony canal into scala media and scala tympani is:
  a) Reticular lamina
  b) Reissner’s membrane
  c) Basilar membrane
  d) Tympanic membrane

• 13. Minimum urine osmolarity that can be achieved by human kidney:
  a) 100 mOsm/L
  b) 50 mOsm/L
  c) 80 mOsm/L
  d) 20 mOsm/L

• 14. Which part of the brain allows us to control skilled voluntary muscle movements?
  a) Basal nuclei
  b) Precentral gyrus
  c) Cerebellum
  d) Thalamus

• 15. Renshaw cell inhibition is an example of:
  a) Positive feedback inhibition
  b) Negative feedback inhibition
  c) Feed-forward inhibition
  d) Postsynaptic inhibition

• 16. Mossy fibers in cerebellum make direct connections with:
  a) Granule cells
  b) Stellate cells
  c) Purkinje cells
  d) Basket cells

• 17. Inability of kidneys to concentrate or dilute urine is:
  a) Anuria
  b) Oliguria
  c) Uremia
  d) Isosthenuria

• 18. Which of the following increases secretion of GH?
  a) Senescence
  b) Somatostatin
  c) Insulin-like growth factor-1
  d) Hypoglycemia

• 19. Which of the following would be associated with parallel changes in aldosterone and cortisol secretion?
  a) Addison’s disease
  b) Cushing’s disease
  c) Cushing’s syndrome (adrenal tumor)
  d) A low-sodium diet

• 20. What accompanies sloughing of the endometrium during the endometrial cycle in a normal woman?
  a) An increase in progesterone
  b) A decrease in both progesterone and estrogen
  c) The LH “surge”
  d) An increase in estradiol

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW

MBBS DEGREE EXAMINATION - 1st PROFESSIONAL - NOV. - 2023

PHYSIOLOGY - PAPER - II

Time: 3 Hrs
Max. Marks: 100 Marks (80 Theory + 20 MCQs)

NOTE:

• Attempt all questions.

• This question paper consists of two sections: Section A - Multiple Choice Questions and Section B - Theory Questions.

• Both sections have different paper codes. Write the correct paper code on the respective sheet.

• Write the correct MCQ paper set on the OMR sheet.

• Answer MCQs on the provided OMR sheet and theory questions in the provided answer booklet.

SECTION B - THEORY QUESTIONS

PAPER CODE: 2312230002

Q.1 Long Answer Question (15 Marks)

Enumerate the Ascending Tracts of the Spinal Cord. Explain in detail the pathway of pain. Add a note on the analgesic system of the brain.

Q.2 Clinical Case Scenario Based Structured Question (15 Marks)

A 40-year-old female presented in OPD with a history of neck swelling and weight loss despite an increase in appetite. She also complained of excessive sweating, heat intolerance, anxiety, nervousness, and insomnia. On examination, she had exophthalmos and fine hand tremors.

i) What is the likely diagnosis? (3 Marks)
ii) Describe the synthesis of the hormone responsible for the above condition. (6 Marks)
iii) Explain the pathophysiology of the above condition. (6 Marks)

Q.3 Short Note Questions (Approx 500 Words) (5 × 6 = 30 Marks)

i) Role of Kidney in Acid-Base Balance
ii) Physiological Changes During Pregnancy
iii) Composition and Functions of CSF
iv) Name the Components of Basal Ganglia. Briefly state the features of Parkinson’s disease.
v) Juxta Glomerular Apparatus

Q.4 Short Answer Questions (Within 100 Words) (5 × 4 = 20 Marks)

i) Differentiate between REM and NREM Sleep
ii) Physiological Actions of Glucocorticoids
iii) Hypothalamo-Pituitary-Ovarian Axis
iv) Visual Reflexes
v) Heat Gain Mechanisms

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