Physiology Paper-1 (Supplementary), 2021 MBBS Batch ABVMU Lucknow

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, UTTAR PRADESH
MBBS 1st PROFESSIONAL SUPPLEMENTARY EXAMINATION
PHYSIOLOGY - PAPER - I

TIME: 3 Hrs
Max. Marks: 100

Note: Attempt all questions. Answer Section - A and Section - B in separate answer books. All parts of a question should be answered together.

PART – A

PAPER CODE: 2321130002

Q.1 Long Answer Question (1 x 15 = 15 Marks)

A resident doctor collected the blood sample of an admitted patient in a glass vial for investigations. After filling the pathology form in a few minutes, he saw that the blood had become semisolid and there is some clear fluid around it.

a) What is the physiological phenomenon mentioned above? (2 Marks)
b) What is the clear fluid called? (1 Mark)
c) Explain the mechanism in detail. (5 Marks)
d) What is the role of platelets in this process? (5 Marks)
e) What are the substances used to prevent this process? (4 Marks)

Q.2 Short Notes Questions (within 500 words) (3 x 5 = 15 Marks)

a) Sodium potassium ATPase Pump
b) Neuromuscular Transmission
c) Renin Angiotensin System

Q.3 Short Answer Questions (within 100 words) (5 x 2 = 10 Marks)

a) Positive Feedback mechanism
b) All or None Law
c) Passive immunity
d) Heart Sounds

Q.4 Multiple Choice Questions (1 x 10 = 10 Marks)

• 1. A typical neuron has a resting membrane potential of about:
  a) +40mV
  b) -10mV
  c) -70mV
  d) 0mV

• 2. Saltatory conduction is faster because the depolarization jumps from one __________ to the next.
  a) Node of Ranvier
  b) Axon Hillock
  c) Dendrite
  d) Myelin Sheath

• 3. In skeletal muscle, calcium facilitates contraction by binding to:
  a) Propiomyosin
  b) Troponin
  c) Tropomyosin
  d) Actin

• 4. Facilitated diffusion refers to:
  a) Passive movement along the concentration gradient
  b) Passive movement against the concentration gradient
  c) Transport of molecules through a semipermeable membrane
  d) Active transport through a semipermeable membrane

• 5. Osmotic pressure of plasma is mainly due to:
  a) Hemoglobin
  b) Albumin
  c) Globulin
  d) Fibrinogen

• 6. Apoptosis is:
  a) Programmed cell death
  b) Unprogrammed cell death
  c) Accidental cell death
  d) Traumatic cell death

• 7. Likely Genotype of a person with Blood group A is:
  a) OO
  b) AB
  c) AO
  d) BO

• 8. Principal site of RBC formation in an adult is:
  a) Flat bones
  b) Long bones
  c) Yolk Sac
  d) Liver

• 9. Blood picture in Iron deficiency anemia is:
  a) Normocytic normochromic
  b) Microcytic hypochromic
  c) Normocytic hypochromic
  d) Macrocytic normochromic

• 10. Immediate Hypersensitivity reaction is due to:
  a) Ig M
  b) Ig E
  c) Cytotoxic T Cells
  d) Helper T Cells

PART – B PAPER CODE: 2321230002

Q.1 Long Answer Question (1 x 15 = 15 Marks)

A 64-year-old company president experienced a sudden, crushing chest pain at 4 A.M in the morning. He was pale, sweating profusely and vomiting once. He was admitted to the ICU of a nearby hospital where ECG was taken & it showed ST elevation in leads II, III, and aVF. He is a heavy smoker and also suffers from diabetes and hypertension.

a) What is the likely diagnosis? (2 Marks)
b) Explain the pathophysiology of this condition. (5 Marks)
c) What are the special features of Coronary circulation? (5 Marks)
d) What are cardiac Biomarkers? (3 Marks)

Q.2 Short Notes Questions (within 500 words) (3 x 5 = 15 Marks)

a) Neural regulation of respiration.
b) Acclimatization to high altitude.
c) Mechanism of HCl secretion in stomach.

Q.3 Short Answer Questions (within 100 words) (5 x 2 = 10 Marks)

a) Functions of Surfactant.
b) Oxygen carrying capacity of Blood.
c) Function of Secretin.
d) Enteric nervous system

Q.4 Multiple Choice Questions (1 x 10 = 10 Marks)

• 1. Korotkoff sounds are produced due to:
  a) Aortic Valve closure
  b) Mitral valve opening
  c) Turbulent Blood flow in artery
  d) Streamlined blood flow in artery

• 2. Which of the following is NOT a pacemaker tissue:
  a) SA Node
  b) AV Node
  c) Bundle of His
  d) Intermodal Fibres

• 3. At any instant, largest amount of blood is present in:
  a) Veins
  b) Arteries
  c) Capillaries
  d) Heart

• 4. All of the following causes Respiratory Alkalosis?
  a) Hypoventilation
  b) Hyperventilation
  c) High Carbohydrate levels
  d) Low Hb Content

• 5. Histotoxic Hypoxia occurs in:
  a) Rapid ascent to High altitude
  b) Carbon monoxide poisoning
  c) Cyanide poisoning
  d) Megaloblastic anemia

• 6. Spirometry cannot measure:
  a) Residual Volume
  b) Inspiratory reserve volume
  c) Expiratory reserve volume
  d) Tidal volume

• 7. Which of the following is TRUE about Neonatal Jaundice?
  a) Normally appears on 10th day of life
  b) Due to Hepatic immaturity
  c) Serum level of Unconjugated bilirubin, decreased
  d) Caused by Viral infection of liver

• 8. Intrinsic factor is secreted by:
  a) Hepatocytes
  b) Chief cells
  c) Parietal cells
  d) Mucous neck cells

• 9. Emulsification of fat mainly occurs in:
  a) Oral Cavity
  b) Stomach
  c) Duodenum
  d) Colon

• 10. All are secreted as proenzymes EXCEPT:
  a) Trypsin
  b) Chymotrypsin
  c) Pepsin
  d) Ribonuclease

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