Pharmacology Paper-2 (Main), 2022 MBBS Batch ABVMU Lucknow

MBBS DEGREE - IInd PROFESSIONAL - REGULAR EXAMINATION - DEC 2024 ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY

PHARMACOLOGY - PAPER - II

SECTION A - Multiple Choice Questions (MCQs)

PAPER CODE: 2412130005 SET: D

Note: Choose one correct answer in the OMR sheet provided. No overwriting should be done.

Time: 20 Minutes (20 x 1 = 20 MARKS)

1 Drug used in heparin overdose is:

a) Phylloquinone b) Ticlopidine c) Clopidogrel d) Protamine sulfate

2 All of the following antidiabetic drugs act by enhancing insulin secretion except

a) Sitagliptin b) Rosiglitazone c) Repaglinide d) Exenatide

3 Antiemetic effect of metoclopramide is mainly due to its action as:

a) D2 antagonist b) M3 antagonist c) 5HT4 agonist d) 5HT3 antagonist

4 Which of the following is a potassium channel opener?

a) Ranolazine b) Ivabradine c) Nitroprusside d) Nicorandil

5 Thalidomide can be used in all of the following conditions except

a) HIV associated peripheral neuropathy b) HIV associated mouth ulcers c) Erythema nodosum leprosum d) Behcet syndrome

6 Aspirin prolongs bleeding by inhibiting the synthesis of which of the following?

a) Cyclic AMP b) Prostacyclin c) Thromboxane A2 d) Adenosine receptors

7 Drug of choice for ventricular tachycardia in a patient with myocardial ischemia is

a) Lignocaine b) Diltiazem c) Digitalis d) Propranolol

8 Voriconazole is not effective against:

a) Mucormycosis b) Candida tropicalis c) Aspergillosis d) Candida albicans

9 Which of the following antimalarial drugs is a slow acting schizonticide?

a) Mefloquine b) Pyrimethamine c) Quinine d) Artemether

10 The most appropriate drug used for chelation therapy in beta thalassemia major is

a) Oral deferiprone b) Intramuscular EDTA c) Oral Succimer d) Oral desferrioxamine

11 A person is being treated for Human Immunodeficiency Virus-1. He developed hypertriglyceridemia and hypercholesterolemia. Most likely drug implicated for these adverse effects is

a) Raltegravir b) Didanosine c) Efavirenz d) Ritonavir

12 Conversion of T4 to T3 is inhibited by all except:

a) Propylthiouracil b) Amiodarone c) Methimazole d) Propranolol

13 Which of the following drug is NOT a GpIIb/IIIa antagonist?

a) Abciximab b) Eptifibatide c) Prasugrel d) Tirofiban

14 All of the following are the adverse effects of Tacrolimus except

a) Neurotoxicity b) Hirsutism c) Hyperglycemia d) Nephrotoxicity

15 Which drug is likely to cause flagellated pigmentation of skin?

a) Minocycline b) Vincristine c) Daunorubicin d) Bleomycin

16 Methotrexate should be given with which of the following to decrease its side effects?

a) Cyanocobalamin b) Thiamine c) Folinic acid d) Folic acid

17 Drug of choice for acyclovir resistant herpes is:

a) Gancyclovir b) Valacyclovir c) Foscarnet d) Cidofovir

18 In leprosy, the best bactericidal agent is?

a) Dapsone b) Rifampicin c) Ethionamide d) Clofazimine

19 Drug given for metoclopramide induced dystonic reaction is

a) Promethazine b) Chlorpromazine c) Prochlorperazine d) Pheniramine

20 All of the following drugs have activity against hepatitis B virus except:

a) Zidovudine b) Emtricitabine c) Telbivudine d) Lamivudine

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY

MBBS DEGREE - IInd PROFESSIONAL - REGULAR EXAMINATION - DEC 2024 PHARMACOLOGY - PAPER - II

Max. Marks: 100 Marks (80 Theory + 20MCQs)

TIME: 3 Hrs

NOTE:

Attempt all questions. This question paper consists of two sections: Section A- Multiple Choice Questions and Section B- Theory Questions. Both the section has different paper code. Write correct paper code on respective sheet.

Write correct MCQ paper set on OMR sheet.

Answer MCQs on the provided OMR sheet and theory questions on the provided answer booklet.

SECTION B - THEORY QUESTIONS

PAPER CODE: 2412230005

Q.1 Long Answer Question. ( 15 MARKS )

(i) Classify anti-malarial drugs. 3 marks

(ii) Mechanism of action and Pharmacological actions of chloroquine 3 marks

(iii) Therapeutic uses and adverse effects of chloroquine. 3 marks

(iv) Advantages and Pharmacological rational of ACT therapy 3 marks

(v) Management of Cerebral Malaria. 3 marks

Q.2 Clinical Case Scenario based Structured Question (15 MARKS)

A 60 year old male came with severe chest pain, sweating and his ECG showed features of myocardial infarction and investigations showed raised LDL.

(i) Discuss the drug therapy in myocardial infarction. 5 marks

(ii) Classify Hypolipidemic agents. 5 marks

(iii) Discuss in detail the mechanism of action, uses and adverse effects of Statins. 5 marks

Q.3 Short Note Question (Approx 500 Words) 5 X 6 = 30 MARKS

(i) Hormone replacement therapy in menopause.

(ii) Write on the mechanism of action, uses and adverse effects of Metformin.

(iii) List out the antiplatelet agents and elaborate on their uses with rationale.

(iv) Mechanism of action, uses & management of adverse effects of Methotrexate

(v) Therapeutic uses and adverse effects of Amphotericin B

Q.4 Short Answer Questions (Within 100 Words) 5 X 4 = 20 MARKS

(i) Treatment of acne vulgaris.

(ii) Clinical uses of Uterine relaxants

(iii) Post exposure prophylaxis (PEP) of HIV infection.

(iv) Differentiate the mechanism of action of Spironolactone and Amiloride and what are their therapeutic uses.

(v) Flouroquinolones and their Therapeutic uses

VitalText Publication - All Rights Reserved