Pharmacology Paper-2 (Main), 2021 MBBS Batch ABVMU Lucknow

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW

MBBS DEGREE - IInd PROFESSIONAL - REGULAR EXAMINATION - MARCH 2024

PHARMACOLOGY - PAPER - II

SECTION A- Multiple Choice Questions (MCQs)

PAPER CODE: 2412130005

SET: D

Time: 20 Minutes

Note: Choose one correct answer in the OMR sheet provided. No overwriting should be done.

(20 x 1 = 20 MARKS)

1. Find the drug which has been associated with aplastic anaemia as a deadly adverse effect.

   a) Chloramphenicol b) Chloroquine c) Ampicillin d) Tetracycline

2. Which one of the following compounds kills bacteria by damaging the cell wall of bacteria?

   a) Gentamicin b) Chloramphenicol c) Cefixime d) Rifampicin

3. All of the following drugs are bactericidal except:

   a) Ciprofloxacin b) Daptomycin c) Tigecycline d) Isoniazid

4. Which of the following drug is not used in osteoporosis?

   a) Denosumab b) Strontium ranelate c) Milnacipran d) PTH

5. Which of the following drug is used mainly to lower post-prandial blood glucose levels?

   a) Sulfonylurea b) Repaglinide c) Acarbose d) Sitagliptin

6. Which one of the following agents belongs to Fusion inhibitor, agent class of antiretroviral drugs?

   a) Ritonavir b) Lamivudine c) Enfuvirtide d) Abacavir

7. Conversion of T4 to T3 is inhibited by all except:

   a) Methimazole b) Amiodarone c) Propylthiouracil d) Propranolol

8. The preferred diuretic for mobilizing edema fluid in CHF is:

   a) Amiloride b) Metolazone c) Hydrochlorothiazide d) Furosemide

9. Red man syndrome is caused by which drug?

   a) Teicoplanin b) Vancomycin c) Clindamycin d) Linezolid

10. Which antibiotic is primarily bacteriostatic but becomes bactericidal at higher concentrations:

    a) Ampicillin b) Chloramphenicol c) Tetracycline d) Erythromycin

11. Which of the following drug is NOT a GpIIb/IIIa antagonist?

    a) Prasugrel b) Eptifibatide c) Abciximab d) Tirofiban

12. Hypothyroidism is a possible consequence of prolonged therapy with:

    a) Procainamide b) Sotalol c) Mexiletine d) Amiodarone

13. Drug of choice for precocious puberty in girls is:

    a) Medroxy progesterone acetate b) Cyproterone acetate c) Danazol d) GnRH analogue

14. Which is an oral factor Xa inhibitor?

    a) Fondaparinux b) Argatroban c) Dabigatran d) Rivaroxaban

15. Which one of the following anticancer drugs belongs to the alkylating agents subdivision of chemotherapeutic agents?

    a) Mercaptopurine b) Procarbazine c) Vincristine d) Paclitaxel

16. Which of the following drug has dual action on HIV and hepatitis B virus?

    a) Acyclovir b) Abacavir c) Emtricitabine d) Enfuvirtide

17. All of the following drugs act on nucleic acids except:

    a) Nalidixic acid b) Rifampicin c) Linezolide d) Fluoroquinolones

18. Which of the following hypolipidemic drugs is most effective in raising HDL-cholesterol level and lowers serum triglycerides:

    a) Pravastatin b) Cholestyramine c) Fenofibrate d) Nicotinic acid

19. Which anti-tubercular drug can result in peripheral neuropathy due to deficiency of pyridoxine?

    a) Pyrazinamide b) Ethambutol c) Rifampicin d) Isoniazid

20. The following quinolone antimicrobial agent is not useful in systemic infections:

    a) Pefloxacin b) Nalidixic acid c) Ofloxacin d) Lomefloxacin

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW

MBBS DEGREE - IInd PROFESSIONAL - REGULAR EXAMINATION - MARCH 2024

PHARMACOLOGY - PAPER - II

Max. Marks: 100 Marks (80 Theory + 20MCQS)

TIME: 3 Hrs

NOTE:

Attempt all questions.

This question paper consists of two sections: Section A- Multiple Choice Questions and Section B- Theory Questions.

Both the section has different paper code. Write correct paper code on respective sheet

Write correct MCQ paper set on OMR sheet

Answer MCQs on the provided OMR sheet and theory questions on the provided answer booklet.

SECTION B - THEORY QUESTIONS

PAPER CODE: 2412230005

Q.1 Long Answer Question (15 Marks)

i) Classify corticosteroids. 3 marks

ii) Describe its pharmacological actions. 4 marks

iii) Therapeutic uses and adverse effects of glucocorticoids. 8 marks

Q.2 Clinical Case Scenario based Structured Question (15 Marks)

A 50-year-old man presented with complaints of tightness and discomfort over middle part of chest felt episodically, particularly after walking briskly or climbing stairs. 1 A diagnosis of stable angina was made.

i) Which drugs should be used at the time of acute episode of angina and mention its rationale. 4 marks

ii) Classify the drugs used for this condition. 4 marks

iii) Which drug groups are recommended for prophylaxis and mention their rationale. 4 marks

iv) Describe coronary steal phenomenon. 3 marks

Q.3 Short Note Questions (Approx 500 Words) (5 x 6 = 30 Marks)

i) Cell wall synthesis inhibitors

ii) Thiazide diuretics

iii) Antiamoebic drugs

iv) Human Insulin

v) Parenteral iron therapy

Q.4 Short Answer Questions (Within 100 Words) (5 x 4 = 20 Marks)

i) Compare and contrast Aspirin vs Clopidogrel

ii) Drug therapy of hypertension in pregnancy

iii) Drug therapy for the treatment of H. pylori induced chronic peptic ulcer

iv) Low molecular weight heparin

v) Compare and contrast Atorvastatin vs Rosuvastatin

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