Pathology Paper-2 (Main), 2021 MBBS Batch ABVMU Lucknow

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW

MBBS DEGREE - IInd PROFESSIONAL - REGULAR EXAMINATION - MARCH 2024

PATHOLOGY - PAPER II

SECTION A - Multiple Choice Questions (MCQs)

PAPER CODE: 2412130004 SET: C

Time: 20 Minutes (20 x 1 = 20 MARKS)

Note: Choose one correct answer on the OMR sheet provided. No overwriting should be done.

1. Neurofibrillary tangles are characteristically seen in
   a) Parkinson's disease
   b) Multiple sclerosis
   c) Alzheimer's disease
   d) Prion disease

2. MEN 1 syndrome includes all except:
   a) Parathyroid hyperplasia
   b) Pituitary adenoma
   c) Pancreatic tumor
   d) Pheochromocytoma

3. Hirschsprung's disease requires histological confirmation for the loss of:
   a) Villi
   b) Muscularis
   c) Stromal layer
   d) Ganglion cells

4. Steroid-resistant nephrotic syndrome is caused by a mutation in gene encoding:
   a) Podocin
   b) Nephrin 1
   c) Alpha-actinin 4
   d) Nephrin 2

5. Gluten intolerance is seen in:
   a) Celiac disease
   b) Whipple's disease
   c) Short bowel syndrome
   d) Tropical sprue

6. Which is the commonest tumor of the uterus?
   a) Leiomyoma
   b) Adenocarcinoma
   c) Fibroadenoma

7. Gleason's score is related to carcinoma of:
   a) Pancreas
   b) Pituitary gland
   c) Prostate
   d) Parathyroid gland

8. The commonest morphological variant of RCC is:
   a) Granular cell type
   b) Papillary type
   c) Sarcomatoid type
   d) Clear cell type

9. Lesion of thyroid associated with viral etiology is:
   a) Graves' thyroiditis
   b) Hashimoto's thyroiditis
   c) DeQuervain's thyroiditis

10. Reactivated TB is most commonly located near:
    a) Bronchioles
    b) Lung apex
    c) Base
    d) Subpleural

11. Flexner-Wintersteiner rosettes are seen in:
    a) Neuroblastoma
    b) Retinoblastoma
    c) Medulloblastoma
    d) Ependymoma

12. In obstructive jaundice, LFTs usually show:
    a) Elevated direct bilirubin
    b) Elevated indirect bilirubin
    c) Elevated direct bilirubin and ALT
    d) Elevated indirect bilirubin and alkaline phosphatase

13. Toxic megacolon is seen in:
    a) Celiac disease
    b) Ulcerative colitis
    c) Appendicitis
    d) Crohn's disease

14. Elevated c-ANCA is seen in:
    a) Polyarteritis nodosa
    b) Wegener's granulomatosis
    c) Microscopic polyangiitis

15. Increased serum calcitonin is observed in:
    a) Medullary carcinoma
    b) Follicular carcinoma
    c) Anaplastic carcinoma
    d) Papillary carcinoma

16. Peutz-Jeghers polyp is commonly located at:
    a) Appendix
    b) Colon
    c) Jejunum
    d) Stomach

17. Ferruginous bodies are seen in:
    a) Asbestosis
    b) Silicosis
    c) Bagassosis
    d) Byssinosis

18. Tumor of bone that usually affects children and adolescents is:
    a) Ewing's sarcoma
    b) Osteosarcoma
    c) Chondrosarcoma

19. Sclerosing retroperitoneal fibrosis is related to:
    a) IgA
    b) IgM
    c) IgG2
    d) IgG4

20. Libman-Sacks endocarditis is found in:
    a) Syphilis
    b) SLE
    c) Lymphoma
    d) Rheumatoid arthritis

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW

MBBS DEGREE - IInd PROFESSIONAL - REGULAR EXAMINATION - MARCH 2024

PATHOLOGY - PAPER - II

TIME: 3 Hrs Max. Marks: 100 Marks (80 Theory + 20 MCQs)

NOTE:

• Attempt all questions.

• This question paper consists of two sections: Section A) Multiple Choice Questions and Section B) Theory Questions.

• Both the sections are on different paper codes. Write the correct paper code on the respective sheet.

• Answer MCQs on the provided OMR sheet and theory questions on the provided answer booklet.

SECTION B - THEORY QUESTIONS

PAPER CODE: 2412230004

Q.1 Long Answer Question (15 Marks)

i) Define Diabetes Mellitus. (2 marks)
ii) Describe its various types. (5 marks)
iii) Outline the components of a complete laboratory workup for diagnosing and monitoring it. (5 marks)
iv) Discuss the potential complications associated with the condition. (3 marks)

Q.2 Clinical Case Scenario based Structured Question (15 Marks)

A 60 years old post-menopausal female presents with a hard lump of 8×8 cm with peau d’orange appearance in the outer upper quadrant of the right breast. FNAC revealed clusters of pleomorphic cells.

i) What is the probable diagnosis? (2 marks)
ii) Discuss the laboratory workup as well as enumerate possible spread sites of this disease. (5 marks)
iii) Discuss the prognostic and predictive features of the disease. (5 marks)
iv) Discuss the relevance of hormonal receptors in this disease. (3 marks)

Q.3 Short Note Question (Within 500 Words) (5 x 6 = 30 Marks)

i) Peptic Ulcer
ii) Alcoholic Liver Disease
iii) Bronchial Asthma
iv) Differentiate between Ulcerative Colitis and Crohn’s Disease
v) Benign Prostatic Hyperplasia

Q.4 Short Answer Questions (Within 100 Words) (5 x 4 = 20 Marks)

i) Premalignant lesions of Oral Cavity
ii) CSF findings in Pyogenic Meningitis
iii) Teratoma Testes
iv) Rapidly Progressive Glomerulonephritis
v) Osteoarthritis

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