Microbiology Paper-2 (Supplementary), 2021 MBBS Batch ABVMU Lucknow

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW
MBBS DEGREE – IInd PROFESSIONAL – SUPPLEMENTARY EXAMINATION – JUNE 2024
MICROBIOLOGY – PAPER II
SECTION A – Multiple Choice Questions (MCQs)
SET: A
PAPER CODE: 2422130006

Note: Choose one correct answer in the OMR sheet provided. No overwriting should be done.
Time: 20 Minutes
(20 × 1 = 20 MARKS)

1. The following viruses cause zoonotic infections except:
   a) Japanese encephalitis
   b) Yellow fever
   c) Chikungunya
   d) Hepatitis B virus

2. A 30-year-old man comes with a history of repeated episodes of hematuria. On urine examination, a parasitic egg is detected. The infection is most likely to be due to:
   a) Schistosoma haematobium
   b) Schistosoma japonicum
   c) Schistosoma mansoni
   d) Heterophyes heterophyes

3. Which of the following gives alpha hemolysis on blood:
   a) Streptococcus pyogenes
   b) Streptococcus pneumoniae
   c) Staphylococcus aureus
   d) Staphylococcus epidermidis

4. Which serotypes of Chlamydia trachomatis cause lymphogranuloma venereum?
   a) A to C
   b) L1 to L3
   c) D to K
   d) Chlamydophila pneumoniae

5. Leishmania donovani causes:
   a) Sleeping sickness
   b) Kala azar
   c) Chagas disease
   d) Malaria

6. Wool Sorter’s disease is caused by:
   a) Bacillus anthracis
   b) Yersinia pestis
   c) Rhodococcus equi

7. The most commonly used method of isolation of Chlamydia is:
   a) Culture on artificial media
   b) Inoculation into guinea pigs
   c) Culture on Vero cell line
   d) Culture on McCoy cell

8. Wrong about Trichomoniasis is:
   a) Falling leaf motility seen
   b) Whiff test is positive
   c) Discharge is profuse
   d) Causative agent is Trichomonas vaginalis

9. A newborn baby presented with mucopurulent discharge from the eye 8 days after birth, most probable causative agent for this condition is:
   a) Chlamydia trachomatis
   b) Neisseria gonorrhoeae
   c) Staphylococcus aureus
   d) Streptococcus pneumoniae

10. Asteroid bodies are observed in:
    a) Sporotrichosis
    b) Candidiasis
    c) Histoplasmosis
    d) Chromoblastomycosis

11. Oriental sore is caused by:
    a) L. mexicana
    b) L. braziliensis
    c) L. tropicana
    d) L. chagasi

12. Principal toxin responsible for gas gangrene is:
    a) Alpha toxin
    b) Eta toxin
    c) Theta toxin
    d) Delta toxin

13. Hand-foot-mouth disease is caused by:
    a) HSV
    b) Coxsackie virus
    c) Chickenpox
    d) Measles

14. Bipolar staining is characteristic of:
    a) Yersinia pestis
    b) Klebsiella
    c) Proteus
    d) Shigella

15. Etiological agent of soft chancre is:
    a) Treponema pallidum
    b) Chlamydia trachomatis
    c) Haemophilus ducreyi
    d) Herpes simplex virus

16. An outbreak of surgical site infection caused by Staphylococcus aureus has occurred in an ICU. To investigate it, which of the following samples would most likely yield the organism?
    a) Rectal swab
    b) Ear swab
    c) Nasal swab
    d) Throat swab

17. Which of the following is Flesh eating bacteria

    a) Staphylococcus

    b) Clostridium perfringens

    c) Group A streptococcus

    d) Bacteroids

18. A 30 year old man complaints uretheral discharge and painful urination . A gram stain smear of the discharge shows many neutrophils . Some containing gram negative diplococci . The most likely causative agent is :

    a) Treponema pallidium

    b) Neisseria gonorrhoeae

    c) Candida Albicans

    d) Ureoplasma

19. What is the causative agent of Scabies

    a) Sarcoptes scabiei

    b) Candida Albicans

    c)Clostridium perfringens

    d) Staphylococcus

20. Which of the following is common cause of neonatal meningitis

    a) E.coli

    b) Listeria

    c) S.agalactiae

    d) S.pneumonia

Q.1 Long Answer Question 15 MARKS

Discuss in detail the pathogenesis, laboratory diagnosis, and immunoprophylaxis of Mycobacterium tuberculosis.

Q.2 Clinical Case Scenario based Structured Question 15 MARKS

A 5-year-old male child admitted to the ICU with complaints of headache and chills. His mother complained that the child is not able to stand 5 days after the onset of fever. He develops flaccid paralysis of lower limbs and tripod sign is elucidated. On CSF analysis, glucose level and protein level are normal. Microscopic examination of CSF shows 25-40 lymphocytes per microliter and no bacteria seen. Ziehl-Neelsen staining of CSF is negative for Acid-Fast Bacilli.

(i) Mention the organism causing the disease. Enumerate other organisms causing myelitis. (3 Marks)
(ii) Write in detail about the clinical manifestations and lab diagnosis of the disease. (6 Marks)
(iii) Describe prophylaxis of the causative organism. (6 Marks)

Q.3 Short Note Questions (Within 500 Words) 5 × 6 = 30 MARKS

i) Post-Kala Azar Dermal Leishmaniasis
ii) Write clinical features and laboratory diagnosis of rabies.
iii) Write clinical features and laboratory diagnosis of syphilis.
iv) Write in detail about superficial fungal infection.
v) Nosocomial infections

Q.4 Short Answer Questions (Within 100 Words) (5 × 4 = 20 Marks)

i) Antigenic shift in Influenza virus
ii) Neurocysticercosis
iii) Enumerate 4 sexually transmitted diseases.
iv) Mucormycosis
v) Enumerate 4 viruses causing meningitis

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