Microbiology Paper-2 (Supplementary), 2020 MBBS Batch ABVMU Lucknow

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW

MBBS IInd PROFESSIONAL SUPPLEMENTARY EXAMINATION - FEB-2023

MICROBIOLOGY-PAPER-II

TIME: 3 Hrs Max. Marks: 100

Note: Attempt all questions. Answer PART- A and PART - B in separate answer books. All parts of a question should be answered together.

PART-A

PAPER CODE: 2322130006

Q.1 Long Answer Question (1 X 15 = 15 Marks)

Discuss geographical distribution, morphology, life cycle, pathogenicity and laboratory diagnosis of Entamoeba histolytica.

Q.2 Short Notes Questions (within 500 words) (3 x 5 = 15 Marks)

• Pathogenesis of COVID-19.

• Multi Drug Resistant Tuberculosis.

• Antigenic diversity in HIV.

Q.3 Short Answer Questions(within 100 words) (5 x 2 = 10 Marks)

• BCG vaccine.

• WHO Moments of Hand Hygiene.

• Mucormycosis.

• Enumerate four parasites causing anemia.

• Viral transport media.

Q.4 Multiple Choice Questions (10 x 1 = 10 Marks)

• 1. All of the following intestinal nematodes are oviparous except:

• (a) Roundworm

• (b) Strongyloides

• (c) Hookworm

• (d) Enterobius

• 2. Which is the smallest tape worm infecting man:

• (a) Taenia Saginata

• (b) Taenia Solium

• (c) Hymenolepis Nana

• (d) Diphyllobothrium Latum

• 3. Adults worm of which of the following parasites reside in human body cavity:

• (a) Mansonella streptocerca

• (b) Wuchereria Bancrofti

• (c) Brugia Malayi

• (d) M. Ozzardi & M. Perstans

• 4. Congenital toxoplasmosis manifests as:

• (a) Microcephaly

• (b) Microopthalmia

• (c) Hepatosplenomegaly

• (d) All of the above

• 5. Which of the following statements regarding antigenic drift in Influenza viruses is correct:

• (a) Results in many antigenic changes

• (b) Exhibited by only Influenza A viruses

• (c) Due to frame shift mutation in viral genes

• (d) Occurs more frequently than antigenic shift

• 6. The mechanism of dengue virus survival in inter epidemic period is:

• (a) Non Human reservoir

• (b) Dormant phase

• (c) Transovarian transmission in Aedes

• (d) Poor housekeeping in public

• 7. The drug of choice for Pneumocystis jiroveci is:

• (a) Cotrimoxazole

• (b) Amphotericin B

• (c) Micafungin

• (d) Itraconazole

• 8. Other name of Darling's disease:

• (a) Histoplasmosis

• (b) Sporotrichosis

• (c) Chromoblastomycosis

• (d) Rhinosporidiosis

• 9. Rabies is identified by:

• (a) Cowdry bodies

• (b) Negri bodies

• (c) Guarneri bodies

• (d) Paschen bodies

• 10. Germ tube test is diagnostic for:

• (a) Candida auris

• (b) Candida glabrata

• (c) Candida albicans

• (d) Cryptococcus

PART-B PAPER CODE: 2322230006

Q.1 Long Answer Question (1 X 15 = 15 Marks)

Describe the morphology and genomic structure of hepatitis B virus. Write in detail about laboratory diagnosis of HBV infection.

Q.2 Short Notes Questions (within 500 words) (3 x 5 = 15 Marks)

• Rabies prophylaxis.

• Cerebral malaria.

• Cutaneous leishmaniasis.

Q.3 Short Answer Questions(within 100 words) (5 x 2 = 10 Marks)

• Enlist Viral causes of Encephalitis.

• Enumerate four Etiological agents of Fungal respiratory infections.

• Enlist causes of Parasitic Central nervous system infections.

• Hepatitis B vaccine

• Post exposure prophylaxis of HIV.

Q.4 Multiple Choice Questions. ( 10×1=10 Marks)

• 1. All of the following are opportunistic fungal infections, Except:

• (a) Candidiasis

• (b) Sporotrichosis

• (c) Aspergillosis

• (d) Cryptococcosis

• 2. Small pox vaccine was discovered by:

• (a) Edward Jenner

• (b) Paul Ehrlich

• (c) Robert Koch

• (d) Joseph Lister

• 3. Which of the following is an example of live vaccine:

• (a) Tetanus

• (b) Salk Polio

• (c) BCG

• (d) Hepatitis B

• 4. Disease transmitting vector of Japanese encephalitis is:

• (a) Tick

• (b) Mosquito

• (c) Sandfly

• (d) Rodent

• 5. Which of the following Hepatitis virus is a DNA virus:

• (a) Hepatitis A

• (b) Hepatitis B

• (c) Hepatitis C

• (d) Hepatitis E

• 6. Fatal fungal meningitis in patients with AIDS is commonly caused by:

• (a) Cryptococcosis

• (b) Sporotrichosis

• (c) Blastomycosis

• (d) Chromoblastomycosis

• 7. During the window period of patient with AIDS, best diagnostic test is:

• (a) ELISA

• (b) Western Blot

• (c) RT-PCR

• (d) Rapid Test

• 8. A 25 year old male bathed in a pond and about after 10 days developed photophobia, reddening of the eyes and blurring of vision. What is the likely etiological agent:

• (a) E. vermicularis

• (b) D. medinensis

• (c) A. fumigatus

• (d) Acanthamoeba spp.

• 9. E. histolytica can be cultured in:

• (a) MacConkey's Agar

• (b) CLED Medium

• (c) Diamond's Medium

• (d) NNN Medium

• 10. Which of the following mosquito transmits Chickungunya virus?

• (a) Anopheles

• (b) Aedes

• (c) Culex

• (d) None of the above

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