General Medicine Paper-1 (Main), 2020 MBBS Batch ABVMU Lucknow

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW
MBBS DEGREE EXAMINATION - IIIrd PROFESSIONAL - PART-II, FEB 2025
PAPER - I: GENERAL MEDICINE
SECTION A - Multiple Choice Questions (MCQs)
SET: B

PAPER CODE: 2511130011

Note: Choose one correct answer in the OMR sheet provided. No overwriting should be done.

Time: 20 Minutes (20 x 1 = 20 MARKS)

• 1. What is the primary goal of fluid resuscitation in septic shock?
  a) Restore adequate tissue perfusion
  b) Correct electrolyte imbalances
  c) Increase oxygen saturation
  d) Normalize blood glucose levels

• 2. Which lab test best differentiates between iron deficiency anemia and anemia of chronic disease?
  a) Mean corpuscular volume
  b) Reticulocyte count
  c) Serum ferritin
  d) Hemoglobin level

• 3. Which of the following laboratory findings is most consistent with primary hypothyroidism?
  a) Low TSH and elevated T4
  b) Low TSH and low T4
  c) Elevated TSH and elevated T4
  d) Elevated TSH and low T4

• 4. Which of the following is a common acute complication of type 1 diabetes mellitus?
  a) Hypothyroidism
  b) Cushing syndrome
  c) Hypersmolar hyperglycemia
  d) Diabetic ketoacidosis

• 5. Which of the following is the first-line vasopressor in septic shock?
  a) Norepinephrine
  b) Vasopressin
  c) Dopamine
  d) Epinephrine

• 6. Philadelphia chromosome is most commonly associated with which leukemia?
  a) Acute lymphoblastic leukemia
  b) Chronic lymphocytic leukemia
  c) Chronic myeloid leukemia
  d) Acute myeloid leukemia

• 7. Which of the following features best differentiates Hodgkin lymphoma from Non-Hodgkin lymphoma?
  a) Presence of Reed-Sternberg cells
  b) Bone marrow involvement
  c) B symptoms
  d) Peripheral lymphadenopathy

• 8. Which of the following coronary arteries is most commonly involved in an anterior wall myocardial infarction (MI)?
  a) Left anterior descending artery
  b) Posterior descending artery
  c) Right coronary artery
  d) Left circumflex artery

• 9. Which of the following is the most common cause of CKD worldwide?
  a) Glomerulonephritis
  b) Polycystic kidney disease
  c) Diabetes mellitus
  d) Hypertension

• 10. Which opportunistic infection is most commonly associated with HIV when the CD4 count drops below 200 cells/μL?
  a) Pneumocystis pneumonia
  b) Kaposi sarcoma
  c) Toxoplasmosis
  d) Cytomegalovirus retinitis

• 11. Which of the following is most commonly associated with high anion gap metabolic acidosis?
  a) Renal tubular acidosis
  b) Hyperaldosteronism
  c) Diarrhea
  d) Lactic acidosis

• 12. Which feature is more characteristic of Crohn's disease (CD) compared to ulcerative colitis (UC)?
  a) Rectal involvement in all cases
  b) Mucosal inflammation only
  c) Continuous inflammation
  d) Non-caseating granulomas

• 13. What is the minimum duration of fever required to classify it as fever of unknown origin (FUO)?
  a) 3 weeks
  b) 4 weeks
  c) 1 week
  d) 2 weeks

• 14. Which of the following ECG findings is most characteristic of severe hyperkalemia?
  a) Peaked T waves
  b) ST-segment elevation
  c) U waves
  d) Flattened T waves

• 15. Which serological marker indicates active replication of hepatitis B virus and high infectivity?
  a) Anti-HBs
  b) Anti-HBe
  c) HBsAg
  d) HBeAg

• 16. Which electrolyte abnormality is most commonly seen in advanced CKD?
  a) Hyperphosphatemia
  b) Hypocalcemia
  c) Hyperkalemia
  d) All of the above

• 17. What is the primary acid-base disorder in a patient with a pH of 7.32, PCO2 of 50 mmHg, and HCO3- of 24 mEq/L?
  a) Metabolic alkalosis
  b) Respiratory alkalosis
  c) Metabolic acidosis
  d) Respiratory acidosis

• 18. In mitral stenosis caused by rheumatic heart disease, which of the following is the most specific clinical finding?
  a) Wide pulse pressure
  b) Displaced apical impulse
  c) Loud first heart sound
  d) Pansystolic murmur radiating to the axilla

• 19. Which of the following is the most common clinical presentation of portal hypertension?
  a) Hepatomegaly
  b) Jaundice
  c) Ascites
  d) Hepatic encephalopathy

• 20. Which electrolyte abnormality is most commonly associated with AKI?
  a) Hypophosphatemia
  b) Hypercalcemia
  c) Hypokalemia
  d) Hyperkalemia

ATAL BIHARI VAJPAYEE MEDICAL UNIVERSITY, LUCKNOW
MBBS DEGREE EXAMINATION - IIIrd PROFESSIONAL - PART-II, FEB 2025
PAPER - I: GENERAL MEDICINE
TIME: 3 Hrs
Max. Marks: 100 Marks (80 Theory + 20 MCQs)

NOTE:

• Attempt all questions.

• This question paper consists of two sections: Section A - Multiple Choice Questions and Section B - Theory Questions.

• Both sections have different paper codes. Write the correct paper code on the respective sheet.

• Write the correct MCQ paper set on the OMR sheet.

• Answer MCQs on the provided OMR sheet and theory questions in the provided answer booklet.

SECTION B - THEORY QUESTIONS

PAPER CODE: 2511230011

Q.1 Long Answer Question (15 MARKS)

i) Define diabetes mellitus. (5 marks)
ii) What are the different types of diabetes? (5 marks)
iii) Describe the clinical features and management of Diabetic Ketoacidosis (DKA). (5 marks)

Q.2 Clinical Case Scenario-based Structured Question (15 MARKS)

A 28-year-old male presents to the emergency department with a 4-day history of high-grade fever, severe headache, retro-orbital pain, myalgia, and generalized fatigue. On examination, his temperature is 39.5°C, blood pressure is 90/60 mmHg, and he has a positive tourniquet test. Laboratory investigations reveal the following:
Platelet count: 80,000/mm³, Hematocrit: 48% (baseline: 42%), ALT and AST: Mildly elevated

i) What is the differential diagnosis? (2 marks)
ii) What are the phases of dengue fever? (3 marks)
iii) What are the danger signs of dengue fever? (5 marks)
iv) Describe the management for this patient. (5 marks)

Q.3 Short Note Question (Approx. 500 Words) (5 x 6 = 30 MARKS)

i) Acute rheumatic fever.
ii) Hypothyroidism in pregnancy.
iii) Management of severe malaria.
iv) Portal Hypertension.
v) Megaloblastic anemia.

Q.4 Short Answer Questions (Within 100 Words) (5 x 4 = 20 MARKS)

i) Hyponatremia.
ii) Pre-renal AKI.
iii) High anion gap metabolic acidosis.
iv) Chronic Myeloid Leukemia (CML).
v) SGLT-2 inhibitors

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