Biochemistry Paper-2 (Main), 2020 MBBS Batch ABVMU Lucknow

MBBS: Biochemistry Paper 2 Part 2 ABVMUUP Paper Code: 211 22 30003

Q1. Give an account of sources, chemistry, functions, RDA and deficiency manifestations of ascorbic acid (Vit. C) & Vit. B12. (20 marks)

Q2. Write briefly on (4X5=20)

a) Glycogen storage diseases

b) Detoxification by conjugation

c) Tumor markers

d) Biological effects of glucocorticoids

Q3. Multiple choice questions (1X10=10)

a) Branched chain keto acids are excreted in urine in large quantities in

A. Phenylketonuria

B. Maple syrup urine disease

C. Tyrosinosis

D. Hartnup’s disease

b) Cholecalciferol is synthesized in

A. Liver

B. Skin

C. Kidney

D. Intestinal mucosa

c) Vitamin K is inhibited by

A. Isoniazid (INH)

B. Methotrexate

C. Dicoumarol

D. Avidin

d) Basal metabolic rate is increased by all the following, EXCEPT

A. Fever

B. Thyroxine

C. Starvation

D. Cold climate

e) All the following diseases may be associated with obesity, EXCEPT

A. Grave’s disease

B. Cushing’s syndrome

C. Depressive psychosis

D. Diabetes mellitus

f) Which is a feature of hypothyroidism?

A. Decreased T3 level in blood

B. Decreased TSH levels

C. Weight loss

D. Increased basal metabolic rate

g) Oncogenes may be activated by all, EXCEPT

A. Viral infection

B. Promotor insertion

C. Mutations in proto-oncogene

D. Reverse transcriptase

h) All the following hormones have membrane receptors, EXCEPT

A. Insulin

B. Epinephrine

C. Glucagon

D. Thyroxine

A. Zidovudine

B. 6-mercaptopurine

C. Allopurinol

D. Acyclovir

i) Which is an anticancer drug?

h) All the following hormones have membrane receptors, EXCEPT

A. Glucose

B. Palmitic acid

C. Albumin

D. Ethanol

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